Coding
AgrA2

Part:BBa_K3183004

Designed by: David Schramm   Group: iGEM19_Oxford   (2019-10-16)
Revision as of 20:57, 20 October 2019 by Mrfelf (Talk | contribs)


AgrA2 Quorum Sensing Transcription Factor; C. difficile

Quorum sensing transcription factor from C. difficile. It is one of the members of the two-component detection system, adapted from C. difficile, that is bound by AgrC2 in response to Autoinducing peptide (AIP), which phosphorylates it. The released phosphorylated AgrA2 dimerizes with itself and becomes active. Upon activation, it binds to AgrPromoter (BBa_K3183003) which results in upregulation of transcription.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


Use by Team Oxford 2019

This transcription factor is part of our detection system in L. reuteri. The composite parts containing this AgrA2 protein are BBa_K3183102, and BBa_K3183300.

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Categories
Parameters
None