Part:BBa_K5184069
G1M5-Cs1A-his
In order to eliminate T.urticae of infested cultivations, spider venom peptide G1M5-Cs1A-his is incorporated in our project with pesticidal means. Cs1a is a small cysteine-rich venom peptide derived from Calommmata signata. Utilized as predatory toxin in nature, it carries the ability to cause paralysis and death in susceptible subjects by blocking voltage-gated calcium channels of them. Having the voltage-gated calcium channels playing a fundamental role in the neuronal system, targets experience fast immobilization after envenomation, thus it serves as an effective pesticide. Due to the cysteine-rich nature of Cs1A, expression strategy that exterminates inclusion bodies is required, thus a G1M5 secretion system is engineered with Cs1A to achieve this. Considering future pesticidal control, G1M5-Cs1A-his can provide future iGEM teams that dedicate in exterminating other destructive pests more choices of sustainable pesticide that could be expressed correctly in Escherichia Coli.
Sequence and Features
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]
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