Signalling

Part:BBa_K3959002

Designed by: Richard Hou   Group: iGEM21_THIS-China   (2021-10-01)
Revision as of 08:49, 14 October 2021 by Richardhou (Talk | contribs)


CSP-1 Competence Signalling Peptide-1 in S.mutans

CSP is a 17 amino acid long small-peptide pheromone ribosomal synthesized and secreted by Streptococcus mutans and Strptococcus pneumoniae, which is a quorum sensing molecule that is commonly found in human dental plaque.

T--THIS-China--CSP picture.png

CSP can be detected by other S. mutans bacteria and leads them to release toxins that kill surrounding bacteria in order to help other S. mutans bacteria form a biofilm on the teeth surface. It regulates gene expression by interacting with ComD and ComE.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


[edit]
Categories
Parameters
None