Protein_Domain
Part:BBa_K3264002
Designed by: Xinyou Chang Group: iGEM19_GreatBay_SZ (2019-10-16)
CT(C-terminal domain of spidroin)
Minispidroin contains an CT from A.ventricosus MiSp E. australis(minor ambulate spidorins). The C-terminal domain is a non-repetitive domain that is highly soluble and pH sensible. In pH=7 solution, it’s a folded dimeric domain, however, as pH decreases, it starts to unfold. The unfolding process was hyposized to generate the formation amyloid-like fibrils that enables transition of the Rep (the repetitive region) into beta-sheet corroboration.
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