Regulatory
p(osmY)
Part:BBa_J45992
Designed by: Stephen Payne Group: iGEM06_MIT (2006-07-11)
Full-length stationary phase osmY promoter
BBa_J45992 is a stationary phase promoter derived from the promoter that controls transcription of osmY in Escherichia coli Yim-1992, Yim-1994<cite>. BBa_J45992 is active in stationary phase and under high osmotic pressure conditions.
Usage and Biology
Expression of osmY is dependent on σS in vivo <cite>Hengge-Aronis-1993. Schellhorn et al. previously demonstrated that an osmY::lacZ fusion generated the highest transcriptional signal in stationary phase as compared to nine other σS-dependent promoter-lacZ fusions Schellhorn-1998, Vijayakumar-2004. In addition, the osmY::lacZ fusion generated only a small transcriptional signal during exponential growth.
<biblio>
- Yim-1994 pmid=8282684
- Yim-1992 pmid=1317380
- Hengge-Aronis-1993 pmid=8416901
- Vijaykumar-2004 pmid=15576800
- Schellhorn-1998 pmid=9829938
</biblio>
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]
[edit]
Categories
Parameters
//chassis/prokaryote/ecoli
//direction/forward
s
//promoter
//regulation/constitutive
//rnap/prokaryote/ecoli/sigmaS
//direction/forward
s
//promoter
//regulation/constitutive
//rnap/prokaryote/ecoli/sigmaS
negative_regulators | |
positive_regulators |