Protein_Domain
Part:BBa_K4175004
Designed by: Li Xianxiu, Zhang Wanying Group: iGEM22_ZJUintl-China (2022-08-28)
CD8 hinge domain
Together with CD8 transmembrane domain (BBa_K4175005), this part is used to connect anti-CD19 single chain variable fragment (scFv) with intracellular signaling motifs (e.g., 4-1BB and CD3ζ in the second-generation CAR). In our project, this basic part is used in the composite part, anti-CD19 CAR (BBa_K4175012).
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]
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Categories
Parameters
biology | Human |