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  • ...a Kcat of 0.045mol/s and a catalytic efficiency of 21,430 per mol second. (Dong et al, 2017, Molecular basis for the substrate specificity of quorum signal In the paper on BjaI (Dong et al 2017), a number of Alanine substitutions were explored that drastical
    28 KB (4,521 words) - 10:42, 1 October 2024
  • ...ce T infiltration through suppression of the interleukin-6(IL-6) signaling pathway. IL-6 is one of the major cytokines in tumor microenvironment that has been ...ironment for CAR-T infiltration. Moreover, it is known that the IL-6/STAT3 pathway facilitates immunosuppression through downregulation of human leukocyte ant
    3 KB (482 words) - 17:33, 29 September 2022
  • * Section of the peptide is mediated via the secretory (Sec) pathway. ...ulatory protein functioning dually as either activator or inhibitor of the pathway [35], [38]. If lactate is not present in environment then translation of ll
    59 KB (8,345 words) - 09:22, 2 October 2024
  • ...o be changed to be able to sense the desired compound and a single gene or pathway that produces the desired compound. Consequently, the system is convenientl ...yield of AdoCbl, the naturally occurring gene <i>bluB</i> of the synthesis pathway of <i>sinorhizobium meliloti</i> 2011 [3].
    35 KB (5,319 words) - 14:18, 12 October 2023
  • ...IFN-&#947;, thereby inhibiting the rate-limiting enzyme of the kynurenine pathway, IDO. This inhibition results in decreased downstream synthesis of NAD and ...Induced Reduction of Interferon-&#947; and Its Implications for Kynurenine Pathway in Major Depressive Disorder. Medical Hypotheses, 83(3), 210-215.
    5 KB (743 words) - 09:46, 21 September 2024
  • :'''Figure 1. HCHO stress response pathway in Arabidopsis.''' ...candidate and tested their regulatory functions in Fungal Bioluminescence Pathway (FBP) via eGFP and GUS reporter system (pS1300-GFP, pS1300-GUS plasmid). Th
    6 KB (923 words) - 03:25, 24 September 2024
  • ...lyA). It is used to target proteins for secretion via the Type I secretion pathway of gram-negative bacteria. Fusion of the HlyA signal peptide to the target ...lyA). It is used to target proteins for secretion via the Type I secretion pathway of gram-negative bacteria. Fusion of the HlyA signal peptide to the target
    6 KB (878 words) - 18:53, 23 October 2020
  • ...phate pathway. Glucose-6-Phosphate-Dehydrogenase is the key enzyme to this pathway [4]. <li>Sang-Jun L.; Young-Mi J.; Hyun-Dong S.; Yong-Hyun L.: Amplification of the NADPH-related genes <i>zwf</i> and <
    20 KB (2,765 words) - 21:05, 18 September 2015
  • ...ansfer (EET). The most wel lcharacterized microbial EET pathway is the Mtr pathway of <i>S. oneidensis</i> MR-1. S. oneidensis MR-1 transfers electrons from t [2] Liang Shi, Dong Hailiang, Reguera Gemma, et al. Extracellular electron transfer mechanisms
    2 KB (272 words) - 06:29, 8 October 2023
  • ...ibit cervical cancer progression through targeting WNT2B by Wnt/β-catenin pathway[2] or miR-145/RCAN3 axis[3] and so on. [1]Yu Furong,Liu Jie,Dong Weilei et al. The diagnostic value of miR-145 and miR-205 in patients with
    3 KB (368 words) - 07:54, 30 September 2023
  • ...Induced Reduction of Interferon-&#947; and Its Implications for Kynurenine Pathway in Major Depressive Disorder. Medical Hypotheses, 83(3), 210-215. ...ge in F-98 Cells by Modulating Neuroinflammation Markers and TREM-2/DAP-12 Pathway. Brain Research, 1821(4), 217-229.
    840 B (101 words) - 09:44, 10 July 2024
  • ...til reaching the final step, which characterizes the de novo DHA-synthesis pathway with a high product specificity. Increased copy number of ACP leads to an i ...2022), Deciphering and engineering the polyunsaturated fatty acid synthase pathway from eukaryotic microorganisms. Front. Bioeng. Biotechnol. 10:1052785. http
    4 KB (588 words) - 22:34, 1 October 2024
  • ...ing efficiency of the AAV-2 decreases with increasing sizes of the insert (Dong, Fan, & Frizzell, 1996), the iGEM team Freiburg_Bioware suggests using the ...ficiently by endogenous guanylate kinase, the second enzyme in the salvage pathway of nucleotides. <br>
    42 KB (5,885 words) - 14:43, 30 October 2010
  • ...eration and Invasion by Targeting E2F Transcription Factor 3. Ma C, Han J, Dong D, Wang N. ...ance. This cell line can be used to further investigate the PDRG signaling pathway to gain a deeper understanding of the molecular mechanisms of TMZ tolerance
    7 KB (1,091 words) - 14:38, 12 October 2022
  • ...bs et al., Correlation between plasma and CSF concentrations of kynurenine pathway metabolites in Alzheimer's disease and relationship to amyloid-beta and tau 18. J. Wu, X. Liu, L. Wang, L. Dong, Q. Pu, An economical fluorescence detector for lab-on-a-chip devices with
    4 KB (467 words) - 02:38, 17 October 2021
  • ...bs et al., Correlation between plasma and CSF concentrations of kynurenine pathway metabolites in Alzheimer's disease and relationship to amyloid-beta and tau 18. J. Wu, X. Liu, L. Wang, L. Dong, Q. Pu, An economical fluorescence detector for lab-on-a-chip devices with
    4 KB (467 words) - 02:44, 17 October 2021
  • ...bs et al., Correlation between plasma and CSF concentrations of kynurenine pathway metabolites in Alzheimer's disease and relationship to amyloid-beta and tau 18. J. Wu, X. Liu, L. Wang, L. Dong, Q. Pu, An economical fluorescence detector for lab-on-a-chip devices with
    4 KB (467 words) - 02:37, 17 October 2021
  • ...bs et al., Correlation between plasma and CSF concentrations of kynurenine pathway metabolites in Alzheimer's disease and relationship to amyloid-beta and tau 18. J. Wu, X. Liu, L. Wang, L. Dong, Q. Pu, An economical fluorescence detector for lab-on-a-chip devices with
    4 KB (467 words) - 02:39, 17 October 2021
  • ...ct as a pro-proliferative protein. By activating the cAMP-protein kinase A pathway, Ca2+ channels open and increase calcium influx, thus DNA synthesis and tum Lu, Y., Zhu, M., Li, W., Lin, B., Dong, X., Chen, Y., Xie, X., Guo, J., & Li, M. (2016). Alpha fetoprotein plays a
    4 KB (578 words) - 11:20, 29 September 2022
  • [1]Yu Furong,Liu Jie,Dong Weilei et al. The diagnostic value of miR-145 and miR-205 in patients with ...cancer progression and metastasis by targeting WNT2B by Wnt/&#946;-catenin pathway.[J] .Int J Clin Exp Pathol, 2019, 12: 3740-3751.
    1 KB (155 words) - 07:11, 30 September 2023

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