Tag

Part:BBa_K3385044

Designed by: Lucas Levassor   Group: iGEM20_DTU-Denmark   (2020-10-12)


SigP_pmeA

About the part: This is the signal peptide for Pectinesterase (pmeA) in Aspergillus niger. The signal peptide was predicted from SignalP-5.0 [1].

Functionality: This signal peptide was investigated in Deeploc [2] to predict the localization of the protein which it is inserted upstream of.

Localization predicted by Deeploc.


Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]

References:
[1] SignalP 5.0 improves signal peptide predictions using deep neural networks. José Juan Almagro Armenteros, Konstantinos D. Tsirigos, Casper Kaae Sønderby, Thomas Nordahl Petersen, Ole Winther, Søren Brunak, Gunnar von Heijne and Henrik Nielsen. Nature Biotechnology, 37, 420-423, doi:10.1038/s41587-019-0036-z (2019)

[2] Jose Juan Almagro Armenteros, Casper Kaae Sønderby, Søren Kaae Sønderby, Henrik Nielsen, Ole Winther; DeepLoc: prediction of protein subcellular localization using deep learning, Bioinformatics, btx431

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