Part:BBa_K3385043

SigP_faeA

About the part: This is the signal peptide for Feruloylesterase A (faeA) in Aspergillus niger. The signal peptide was predicted from SignalP-5.0 [1].

Functionality: This signal peptide was investigated in Deeploc [2] to predict the localization of the protein which it is inserted upstream of.

Localization predicted by Deeploc.

Sequence and Features

Assembly Compatibility:

• 10
  INCOMPATIBLE WITH RFC[10]

  Illegal PstI site found at 44
  
• 12
  INCOMPATIBLE WITH RFC[12]

  Illegal PstI site found at 44
  
• 21
  COMPATIBLE WITH RFC[21]
• 23
  INCOMPATIBLE WITH RFC[23]

  Illegal PstI site found at 44
  
• 25
  INCOMPATIBLE WITH RFC[25]

  Illegal PstI site found at 44
  
• 1000
  COMPATIBLE WITH RFC[1000]

References:
[1] SignalP 5.0 improves signal peptide predictions using deep neural networks. José Juan Almagro Armenteros, Konstantinos D. Tsirigos, Casper Kaae Sønderby, Thomas Nordahl Petersen, Ole Winther, Søren Brunak, Gunnar von Heijne and Henrik Nielsen. Nature Biotechnology, 37, 420-423, doi:10.1038/s41587-019-0036-z (2019)

[2] Jose Juan Almagro Armenteros, Casper Kaae Sønderby, Søren Kaae Sønderby, Henrik Nielsen, Ole Winther; DeepLoc: prediction of protein subcellular localization using deep learning, Bioinformatics, btx431