Coding

Part:BBa_K3100018

Designed by: Zheng Yiyuan   Group: iGEM19_SCUT_China   (2019-10-06)


gadC (antiacid gene)

Usage and Biology:

An amino acid antiporter GadC exchanges extracellular L-glutamate (Glu) with intracellular γ-aminobutyric acid (GABA), but also Gln and L-methionine. GadC can work synergistically with a variety of acid-resistant factors to form an acid-resistant system. It is known that YbaS-GadC is a glutamine-dependent acid-resistant system and GDAR(AR2) is glutamic acid-dependent acid-resistant system [1].

References:


Kanjee U, Houry WA. Mechanisms of acid resistance in Escherichia coli. Annu Rev Microbiol. 2013;67:65–81. 10.1146/annurev-micro-092412-155708.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    INCOMPATIBLE WITH RFC[25]
    Illegal AgeI site found at 1011
    Illegal AgeI site found at 1075
  • 1000
    COMPATIBLE WITH RFC[1000]


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Categories
Parameters
None