Protein_Domain

Part:BBa_K3031005

Designed by: David Doyle   Group: iGEM19_SUIS_Shanghai   (2019-10-13)


Signalling Peptide LP_2145

This peptide is classed as a signal peptide which plays an important role of protein export to the cell membrane or cell wall. Proteins which follow the Sec-dependent pathway are synthesized with a N-terminal signalling peptide that shuttles the protein to the Sec translocation machinery after translation. The signal peptide is then cleaved off during or shortly after the translocation. This signal peptide (SP) sequence belongs to a SP found in the genome of L. plantarum WCFS1 and has been shown to function well at secreting heterlogous proteins in L. plantarum (Matheisn et al,. 2009)

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    INCOMPATIBLE WITH RFC[12]
    Illegal NheI site found at 112
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


[edit]
Categories
Parameters
None