Device

Part:BBa_K2335005

Designed by: zhi ling lui   Group: iGEM17_KAIT_JAPAN   (2017-10-25)


IL-10receptor+STAT1+JAK

A part to operate cure allergic rhinitis system. In order to make this system work, IL-10 secreted from antigen presenting cells must be accepted when pollen is judged as an antigen. Therefore, IL-10receptor of this part accepts IL-10. When IL-10 receptor accepts IL-10, JAK (tyrosine kinase) will be activates and STAT1 will be phosphorylated.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    INCOMPATIBLE WITH RFC[12]
    Illegal NheI site found at 1167
    Illegal NheI site found at 6837
  • 21
    INCOMPATIBLE WITH RFC[21]
    Illegal BglII site found at 6192
    Illegal BglII site found at 6388
    Illegal BglII site found at 6437
    Illegal BamHI site found at 5249
    Illegal BamHI site found at 5309
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    INCOMPATIBLE WITH RFC[25]
    Illegal NgoMIV site found at 4120
    Illegal AgeI site found at 4819
  • 1000
    INCOMPATIBLE WITH RFC[1000]
    Illegal BsaI site found at 1898
    Illegal BsaI.rc site found at 1912
    Illegal BsaI.rc site found at 6776
    Illegal SapI.rc site found at 2293
    Illegal SapI.rc site found at 2328


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Categories
Parameters
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