Signalling
Part:BBa_M41016
Designed by: Laila Shehata Group: MIT BE 20.20-S13 (2013-05-14)
Calcium sensor from Streptococcus mutans
CiaH is a histidine kinase calcium sensor from gram-positive bacteria Streptococcus mutans. CiaH works in conjunction with CiaX (an extracellular calcium-binding peptide) and CiaR (an intracellular reporting molecule that acts as an activator) to control expression of the cia operon. When extracellular calcium concentrations are low, CiaH (activated by unbound CiaX) phosphorylates CiaR, enabling CiaR to act as an activator for the cia operon. Explanation of cia operon: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2955730/
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21INCOMPATIBLE WITH RFC[21]Illegal XhoI site found at 911
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]
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Categories
Parameters
None |