DNA

Part:BBa_M11055

Designed by: Sanjib Kumar Shrestha   Group: UtahState BE5930 - S09 UtahState BE5930 - S10   (2009-04-16)

neo7 gene

2-deoxystraptamine(2-DOS) is a core aglycon that is the vital to backbone formation in various aminoglycoside. This core structure can be modified to develop hybrid types of amninoglycoside antibiotics. There is a single open reading frame in the Streptomyces fradiae genome, that contains three genes neo7,neo6 and neo5. These genes work in concert to produce 2-deoxystraptamine compound. The neo7 gene encodes the enzyme called 2-deoxy-scyllo-inosose synthase which plays vital role in the biosynthesis of the core aglycon, 2-DOS.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    INCOMPATIBLE WITH RFC[25]
    Illegal NgoMIV site found at 601
    Illegal NgoMIV site found at 1140
    Illegal NgoMIV site found at 1212
  • 1000
    INCOMPATIBLE WITH RFC[1000]
    Illegal BsaI.rc site found at 637
    Illegal SapI site found at 351


[edit]
Categories
Parameters
None