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Part:BBa_K902008

Designed by: Himika Dastidar   Group: iGEM12_Calgary   (2012-09-28)

MgtA riboswitch

MgtA riboswitch

The mgtA riboswitch is regulated by the concentration of magnesium in the cell. It provides a post-transcriptional control of gene expression in E. coli responding to the concentration of magnesium in the cell.

With increasing concentrations of magnesium, the magnesium riboswitch is repressed. Cromie and Grosman, 2009 show that the mgtA promoter (BBa_K902009) and the riboswitch are repressed at 10mM MgCl2. However, it is important to remember that the system requires the signal transduction proteins PhoP(BBa_K902010) and PhoQ(BBa_K902011) are necessary to tightly control the system.

This is the mgtA pathway where the mgtA riboswitch plays a role

Magnesium system figure.png


Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


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Categories
Parameters
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