Coding

Part:BBa_K809607

Designed by: Jianhui Gong   Group: iGEM12_Shenzhen   (2012-09-23)

human bax protein

Bax protein belongs to bcl-2 family in human apoptosis pathway. It can turn to homodimer and form pores on the outer mitochondrial membrane and bind to VDAC( voltage-dependent anion channel), making it more permeable, just as holin protein to e.coli. Finally, it triggers apoptosis of human cell and also yeast cell by releasing cytochrome C and other apoptosis factor to cytoplasm. It has the same function with lambda holin(BBa_K809605).

Sequence and Features


Assembly Compatibility:
  • 10
    INCOMPATIBLE WITH RFC[10]
    Illegal PstI site found at 967
    Illegal PstI site found at 1333
    Illegal PstI site found at 1483
    Illegal PstI site found at 1554
    Illegal PstI site found at 3305
    Illegal PstI site found at 3571
    Illegal PstI site found at 4124
  • 12
    INCOMPATIBLE WITH RFC[12]
    Illegal PstI site found at 967
    Illegal PstI site found at 1333
    Illegal PstI site found at 1483
    Illegal PstI site found at 1554
    Illegal PstI site found at 3305
    Illegal PstI site found at 3571
    Illegal PstI site found at 4124
    Illegal NotI site found at 21
  • 21
    INCOMPATIBLE WITH RFC[21]
    Illegal BglII site found at 1517
    Illegal BamHI site found at 160
    Illegal BamHI site found at 3154
    Illegal BamHI site found at 6033
    Illegal XhoI site found at 319
  • 23
    INCOMPATIBLE WITH RFC[23]
    Illegal PstI site found at 967
    Illegal PstI site found at 1333
    Illegal PstI site found at 1483
    Illegal PstI site found at 1554
    Illegal PstI site found at 3305
    Illegal PstI site found at 3571
    Illegal PstI site found at 4124
  • 25
    INCOMPATIBLE WITH RFC[25]
    Illegal PstI site found at 967
    Illegal PstI site found at 1333
    Illegal PstI site found at 1483
    Illegal PstI site found at 1554
    Illegal PstI site found at 3305
    Illegal PstI site found at 3571
    Illegal PstI site found at 4124
    Illegal NgoMIV site found at 147
  • 1000
    INCOMPATIBLE WITH RFC[1000]
    Illegal BsaI site found at 414
    Illegal BsaI site found at 2630
    Illegal BsaI site found at 3428
    Illegal BsaI site found at 3451
    Illegal BsaI site found at 3521
    Illegal BsaI site found at 3900
    Illegal BsaI site found at 3938
    Illegal BsaI.rc site found at 4288
    Illegal BsaI.rc site found at 4754


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Categories
Parameters
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