Part:BBa_K653004

Rhamnose production BioBrick

In addition to the direct use of rhamnolipids, they are also used as commercial sources of rhamnose sugar. It is not ideal to have plants as a source of an industrial compound, since their availability may be limited. Many companies prefer to obtain industrial natural products from genetically engineered sources.

There are myriad other uses for this sugar. For instance, there is an overexpression system in which the production of the desired gene is triggered by adding sterilized rhamnose to the genetically engineered bacteria. A rhamnose test is available for intestinal permeability in humans. Many prescription drugs, such as non-steriodal anti-inflammatory drugs (NSAIDs), can cause intestinal damage that manifests as leakage through the intestines. Having patients drink a solution of lactulose and L-rhamnose is one way of testing for this condition.

With just any carbon source now our modify bacteria along with this rhamnose BioBrick can produce rhamnolipids and many other applications.

Sequence and Features

Assembly Compatibility:

• 10
  INCOMPATIBLE WITH RFC[10]

  Illegal PstI site found at 1198
  Illegal PstI site found at 1738
  Illegal PstI site found at 3407
  
• 12
  INCOMPATIBLE WITH RFC[12]

  Illegal PstI site found at 1198
  Illegal PstI site found at 1738
  Illegal PstI site found at 3407
  Illegal NotI site found at 1299
  
• 21
  INCOMPATIBLE WITH RFC[21]

  Illegal BamHI site found at 1157
  Illegal XhoI site found at 2751
  
• 23
  INCOMPATIBLE WITH RFC[23]

  Illegal PstI site found at 1198
  Illegal PstI site found at 1738
  Illegal PstI site found at 3407
  
• 25
  INCOMPATIBLE WITH RFC[25]

  Illegal PstI site found at 1198
  Illegal PstI site found at 1738
  Illegal PstI site found at 3407
  Illegal NgoMIV site found at 119
  Illegal NgoMIV site found at 203
  Illegal NgoMIV site found at 260
  Illegal NgoMIV site found at 719
  Illegal NgoMIV site found at 1030
  Illegal NgoMIV site found at 1926
  Illegal NgoMIV site found at 2757
  
• 1000
  INCOMPATIBLE WITH RFC[1000]

  Illegal BsaI site found at 2793
  Illegal BsaI.rc site found at 830
  Illegal BsaI.rc site found at 881
  Illegal BsaI.rc site found at 1046
  Illegal BsaI.rc site found at 2922