Coding
Part:BBa_K650011
Designed by: David Sweet Group: iGEM11_NYC_Wetware (2011-09-13)
Tpx (E. coli)
Oxidative stress defenses combat reactive oxygen species such as superoxide (O), hydrogen peroxide (H2O2) and the hydroxyl radical (OH) generated by the host immune response, environmental factors, and the incomplete reduction of oxygen to water during aerobic respiration, all of which are hazardous to proteins, DNA, and lipids. E. coli Tpx (thiol peroxidase) is part of an oxidative stress defense system that uses reducing equivalents from thioredoxin (Trx1) and thioredoxin reductase to reduce alkyl hydroperoxides.
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21INCOMPATIBLE WITH RFC[21]Illegal BglII site found at 99
- 23COMPATIBLE WITH RFC[23]
- 25INCOMPATIBLE WITH RFC[25]Illegal AgeI site found at 172
- 1000COMPATIBLE WITH RFC[1000]
[edit]
Categories
Parameters
None |