Coding

Part:BBa_K650011

Designed by: David Sweet   Group: iGEM11_NYC_Wetware   (2011-09-13)


Tpx (E. coli)

Oxidative stress defenses combat reactive oxygen species such as superoxide (O), hydrogen peroxide (H2O2) and the hydroxyl radical (OH) generated by the host immune response, environmental factors, and the incomplete reduction of oxygen to water during aerobic respiration, all of which are hazardous to proteins, DNA, and lipids. E. coli Tpx (thiol peroxidase) is part of an oxidative stress defense system that uses reducing equivalents from thioredoxin (Trx1) and thioredoxin reductase to reduce alkyl hydroperoxides.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    INCOMPATIBLE WITH RFC[21]
    Illegal BglII site found at 99
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    INCOMPATIBLE WITH RFC[25]
    Illegal AgeI site found at 172
  • 1000
    COMPATIBLE WITH RFC[1000]


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Categories
Parameters
None