Part:BBa_K4998048

Antimicrobial peptide

Usage and Biology

This part contains the sequence that expresses an antimicrobial peptide. We took the existing part 2LS1 which has antimicrobial properties against gram-positive bacteria. We added a series of negatively charged amino acids at the N-terminus and one Cysteine near the C-terminus to enhance the crosslinking between two polysaccharides in our hydrogel.

Sequence and Features

Assembly Compatibility:

• 10
  COMPATIBLE WITH RFC[10]
• 12
  COMPATIBLE WITH RFC[12]
• 21
  COMPATIBLE WITH RFC[21]
• 23
  COMPATIBLE WITH RFC[23]
• 25
  COMPATIBLE WITH RFC[25]
• 1000
  COMPATIBLE WITH RFC[1000]

References

[1] G. Michailidou, Z. Terzopoulou, A. Kehagia, A. Michopoulou, and D. N. Bikiaris, “Preliminary Evaluation of 3D Printed Chitosan/Pectin Constructs for Biomedical Applications,” Mar. Drugs, vol. 19, no. 1, pp. 1–18, 2021, doi: 10.3390/MD19010036.

[2] Z. Zhang, “Studying mass and mechanical property changes during the degradation of a bioadhesive with mass tracking, rheology and magnetoelastic ( ME ) sensors,” 2018.