DNA

Part:BBa_K4960018

Designed by: Ziying Wang   Group: iGEM23_NUDT-CHINA   (2023-10-10)


PAU_RS16560
regulates the expression of PVCs gene

Profile

Name: PAU_RS16560
Base Pairs: 297 bp
Origin: Photorhabdus
Properties: regulates the expression of PVCs gene


Usage and Biology

The PVCs contain 16 structural genes (Pvc1–Pvc16), two potential effector genes and three putative open reading frames (ORFs) According to the Pfam prediction,one of the three ORFs (PAU_RS16560) comprises a predicted bacterial regulatory helix-turn-helix DNA binding domain (LysR family, PF00126) [1]
It suggests that this LysR-type protein is a putative transcription regulator, which is necessary and sufficient to promote formation of PVC particles.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]



References

[1] Wang X, Cheng J, Shen J, Liu L, Li N, Gao N, Jiang F, Jin Q. Characterization of Photorhabdus Virulence Cassette as a causative agent in the emerging pathogen Photorhabdus asymbiotica. Sci China Life Sci. 2022 Mar;65(3):618-630.

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