Coding
Part:BBa_K4739012
Designed by: Huaiyuan Ma Group: iGEM23_SUSTech-Shenzhen (2023-10-11)
Tenecteplase, a myocardial peptide drug
Tenecteplase, a thrombolytic agent produced using recombinant DNA technology, is FDA-approved for reducing mortality in ST-elevation acute myocardial infarction (STEMI) patients. It is also used off-label for treating acute ischemic stroke, pulmonary embolism, and clearing central venous catheters. Despite not being FDA-approved for acute ischemic strokes, its use is growing due to advantages like a single-dose intravenous administration and lower cost compared to alteplase. Particularly for stroke treatment, tenecteplase is a more cost-effective option than alteplase in the US market, saving approximately $3000 per dosage.
Sequence and Features
Assembly Compatibility:
- 10INCOMPATIBLE WITH RFC[10]Illegal EcoRI site found at 615
Illegal EcoRI site found at 1087
Illegal PstI site found at 1204 - 12INCOMPATIBLE WITH RFC[12]Illegal EcoRI site found at 615
Illegal EcoRI site found at 1087
Illegal PstI site found at 1204
Illegal NotI site found at 886 - 21INCOMPATIBLE WITH RFC[21]Illegal EcoRI site found at 615
Illegal EcoRI site found at 1087 - 23INCOMPATIBLE WITH RFC[23]Illegal EcoRI site found at 615
Illegal EcoRI site found at 1087
Illegal PstI site found at 1204 - 25INCOMPATIBLE WITH RFC[25]Illegal EcoRI site found at 615
Illegal EcoRI site found at 1087
Illegal PstI site found at 1204 - 1000COMPATIBLE WITH RFC[1000]
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Categories
Parameters
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