Part:BBa_K4683009

hsa-mir-150-5p

Sequence for hsa-mir-150-5p. It is used as the basis for BBa_K4683010 and BBa_K4683011, the 3' arm for mir-150-5p and 5' arm for mir-150-5p, and as the target sequence for BBa_K4683012.
This part is the sequence for hsa-miR-150-5p, an miRNA isolated from Homo sapiens. This miRNA acts as a biomarker for coronary artery disease and is therefore potentially useful for the early detection of this disease. hsa-miR-150-5p is related to the inflammation process and is involved in the pathogenesis of coronary artery disease. Therefore, hsa-miR-150-5p is a means by which cardiologists can monitor the progression of the disease in patients (Zhang et al., 2015).

References:

Kaur, A., Mackin, S. T., Schlosser, K., Wong, F. L., Elharram, M., Delles, C., Stewart, D. J., Dayan, N., Landry, T., & Pilote, L. (2020). Systematic review of microRNA biomarkers in acute coronary syndrome and stable coronary artery disease. Cardiovascular research, 116(6), 1113–1124. https://doi.org/10.1093/cvr/cvz302
Zhang, R., Lan, C., Pei, H., Duan, G., Huang, L., & Li, L. (2015). Expression of circulating miR-486 and miR-150 in patients with acute myocardial infarction. BMC cardiovascular disorders, 15, 51. https://doi.org/10.1186/s12872-015-0042-0

Sequence and Features

Assembly Compatibility:

• 10
  COMPATIBLE WITH RFC[10]
• 12
  COMPATIBLE WITH RFC[12]
• 21
  COMPATIBLE WITH RFC[21]
• 23
  COMPATIBLE WITH RFC[23]
• 25
  COMPATIBLE WITH RFC[25]
• 1000
  COMPATIBLE WITH RFC[1000]