RNA

Part:BBa_K4667012

Designed by: Xuanxin Zhang   Group: iGEM23_BPI-China   (2023-09-29)


miRNA-16

Human miR-16 has been cloned by independent groups. This precursor sequence maps to chromosome 13, and was named mir-16. Lim et al. reported 2 identical chromosome 13 loci, which appear to map to the same locus in subsequent genome assemblies. This gene and miR-15a are clustered within 0.5 kb at 13q14. This region has been shown to be deleted in more than half of B cell chronic lymphocytic leukemias (CLL). Both miR-15a and miR-16 are deleted or down-regulated in more than two thirds of CLL cases. A second putative mir-16 hairpin precursor is located on chromosome 3 (MIR:MI0000738).

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


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