DNA

Part:BBa_K4638011

Designed by: Hao Yu   Group: iGEM23_PekingHSC   (2023-10-04)


HA packaging sequence-3'

The 3’ part of the packaging sequence of Hemagglutinin of WSN

Usage and Biology

Hemagglutinin, often abbreviated as HA, is a crucial protein found on the surface of influenza viruses. The HA protein binds to sialic acid-containing receptors on the host cell surface and mediates the fusion of the viral envelope with the endosomal membrane after receptor-mediated endocytosis. HA packaging sequence is what regulates the amount of HA expressed on the surface of Influenza, and this is the 3’ part of the packaging signal.


Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    INCOMPATIBLE WITH RFC[1000]
    Illegal BsaI site found at 11



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Categories
//dna
Parameters
biologyinfluenza A viruses