Part:BBa_K4612111
hsa-mir-21-5p _Target_11
hsa-mir-21-5p _Target_11 (BBa_K4612111) is a single-stranded DNA sequence with 22 nucleotides, and is a cDNA sequence derived from the reverse transcription of hsa-mir-21-5p. miR-21-5p is a member of the miR-21 family and is involved in the regulation of non-small cell lung cancer. It exerts oncogenic functions by inhibiting many important tumor suppressor genes, such as inhibiting the tumor suppressor PTEN in non-small cell lung cancer to stimulate cell growth and invasion[1]. Therefore, the expression of hsa-mir-21-5p has a role in determining whether or not you have small cell lung cancer, and can be given weight. Figure 1 demonstrates the specific function of this element: it binds to the probe as a target, and then the polymerase undergoes a polymerase-mediated strand displacement reaction using it as a primer. The weighted strand that is displaced is then subjected to a subsequent reaction.
Sequence and Features
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