DNA

Part:BBa_K4612109

Designed by: Zibin Chu   Group: iGEM23_BUCT-China   (2023-08-20)


hsa-mir-182-5p_Target_9

hsa-mir-182-5p_Target_9 (BBa_K4612109) is a single-stranded DNA sequence with 24 nucleotides, and is a cDNA sequence derived from the reverse transcription of hsa-mir-182-5p. miR-182-5p is a member of the miR-182 family and is involved in the regulation of non-small cell lung cancer. It promotes NSCLC progression by targeting EPAS1 and is a potential indicator of tumor recurrence in NSCLC patients[1]. Therefore, the expression of hsa-mir-182-5p has a role in determining whether or not you have small cell lung cancer, and can be given weight. Figure 1 illustrates the specific function of this component: it binds to the probe as a target, and then the polymerase uses it as a primer for a polymerase-mediated strand displacement reaction. The weighted strand is then subjected to a subsequent reaction.
hsa-mir-192-5p
Sequence and Features BBa_K4612109 SequenceAndFeatures

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