Part:BBa_K4594003

luxG

luxG is a gene from Vibrio fischeri ES114, coding FMN reductase. LuxG has been proposed to be a flavin reductase that supplies reduced flavin mononucleotide (FMN) for bacterial luminescence, and LuxG is the most significant source of FMNH⁻ for the luminescence reaction in vivo. [1].

 

Fig1 Comparison of the luminescence of P. leiognathi-luxG knockout and of native P. leiognathi TH1 [1].

 

Fig2 The molecular mechanism of LuxG [2]

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^[1] Nijvipakul, Sarayut et al. “LuxG is a functioning flavin reductase for bacterial luminescence.” Journal of bacteriology vol. 190,5 (2008): 1531-8. doi:10.1128/JB.01660-07

^[2] Brodl, Eveline et al. “Molecular Mechanisms of Bacterial Bioluminescence.” Computational and structural biotechnology journal vol. 16 551-564. 15 Nov. 2018, doi:10.1016/j.csbj.2018.11.003

Sequence and Features

Assembly Compatibility:

• 10
  COMPATIBLE WITH RFC[10]
• 12
  COMPATIBLE WITH RFC[12]
• 21
  COMPATIBLE WITH RFC[21]
• 23
  COMPATIBLE WITH RFC[23]
• 25
  COMPATIBLE WITH RFC[25]
• 1000
  COMPATIBLE WITH RFC[1000]