Part:BBa_K4497003

Interleukin-11 receptor alpha chain signaling sequence

With signaling sequences, a protein can be directed to the appropriate cellular compartment within a cell.

When adding this signaling sequence to your synthetic protein, it is targeted to the cell membrane.

More information can be found here: http://www.signalpeptide.de/index.php?sess=&m=searchspdb&s=details&id=18521&listname=

Sequence and Features

Assembly Compatibility:

• 10
  COMPATIBLE WITH RFC[10]
• 12
  COMPATIBLE WITH RFC[12]
• 21
  COMPATIBLE WITH RFC[21]
• 23
  COMPATIBLE WITH RFC[23]
• 25
  COMPATIBLE WITH RFC[25]
• 1000
  COMPATIBLE WITH RFC[1000]

References

Engelowski, E., Schneider, A., Franke, M., Xu, H., Clemen, R., Lang, A., Baran, P., Binsch, C., Knebel, B., Al-Hasani, H., Moll, J. M., Floß, D. M., Lang, P. A., & Scheller, J. (2018). Synthetic cytokine receptors transmit biological signals using artificial ligands. Nature Communications, 9(1). https://doi.org/10.1038/S41467-018-04454-8