![](https://parts.igem.org/images/partbypart/icon_coding.png)
Part:BBa_K4458011
Aryl Hydrocarbon Receptor Nuclear Translocator(ARNT)
"This gene encodes a protein containing a basic helix-loop-helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand-bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co-factor for transcriptional regulation by hypoxia-inducible factor 1. Chromosomal translocation of this locus with the ETV6 (ets variant 6) gene on chromosome 12 have been described in leukemias. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2013]"
https://www.ncbi.nlm.nih.gov/gene/405
Sequence and Features
- 10INCOMPATIBLE WITH RFC[10]Illegal EcoRI site found at 346
Illegal XbaI site found at 1854
Illegal SpeI site found at 1303 - 12INCOMPATIBLE WITH RFC[12]Illegal EcoRI site found at 346
Illegal NheI site found at 151
Illegal SpeI site found at 1303 - 21INCOMPATIBLE WITH RFC[21]Illegal EcoRI site found at 346
Illegal BamHI site found at 1272 - 23INCOMPATIBLE WITH RFC[23]Illegal EcoRI site found at 346
Illegal XbaI site found at 1854
Illegal SpeI site found at 1303 - 25INCOMPATIBLE WITH RFC[25]Illegal EcoRI site found at 346
Illegal XbaI site found at 1854
Illegal SpeI site found at 1303 - 1000INCOMPATIBLE WITH RFC[1000]Illegal BsaI site found at 583
Illegal BsaI.rc site found at 119
Illegal BsaI.rc site found at 1149
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