Coding

Part:BBa_K3942000

Designed by: Igor Blatov   Group: iGEM21_MIPT_MSU   (2021-10-12)


ERVW-1 gene

ERVW-1 gene is used to express Syncytin-1 protein. Syncytin is expressed in the testicles and placenta, it is needed for the formation of syncytium, therefore, cell fusion. Additionally, it is used in sex cells fusion. Due to its fusion properties, and fact that some cancer types have overabundance of syncytin receptors (e.g. colorectal adenocarcinoma). Therefore, if any team aims to use fusion proteins, or need to specifically aim for cancer cells, this part will present a perfect candidate for such project.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    INCOMPATIBLE WITH RFC[12]
    Illegal NheI site found at 1516
  • 21
    INCOMPATIBLE WITH RFC[21]
    Illegal BglII site found at 447
    Illegal BglII site found at 1487
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    INCOMPATIBLE WITH RFC[1000]
    Illegal BsaI site found at 531
    Illegal SapI.rc site found at 1148
    Illegal SapI site found at 845


[edit]
Categories
Parameters
None