Coding

Part:BBa_K3830003

Designed by: Fang Ti   Group: iGEM21_NCHU_Taichung   (2021-10-16)


PqqB can catalyze the biosynthesis of PQQ


PqqB(Figure A) belongs to the metallo-b-lactamase superfamily . Enzymes

in this superfamily generally catalyze the hydrolysis of small molecules using metal

centers(Figure B) that range from zinc to manganese, nickel, magnesium, and iron . PqqB

serve as an oxygenase to modify the tyrosine side-chain within PqqA.

And it can cross-over between the metallo-b-lactamase superfamily and the nonheme iron

hydroxylases.

T--NCHU_Taichung--NCHU_2021_Figure_O.png

Figure1. The synthesis of AHQQ.



Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    INCOMPATIBLE WITH RFC[12]
    Illegal NheI site found at 166
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


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