RNA

Part:BBa_K3800032

Designed by: Chambre Garcia   Group: iGEM21_Missouri_Miners   (2023-10-03)


Tumor suppressor and biomarker for early detection of breast cancer.

Micro RNAs, or miRNAs, are non-coding regulators of gene expression that act after transcription. Many miRNA have been identified that act in a primarily oncogenic or tumor suppressive manner, which is ideal for highly specific indicators to diagnose cancers at early stages. MiRNA424-5p is a tumor suppressor that is elevated during the early stages of breast cancer and is present in biofluids like urine, which makes it a great target for non-invasive early detection of breast cancer. Early detection of cancer improves prognosis, and miRNA424-5p can also be used to predict how the patient will react to chemotherapy and radiotherapy.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


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Categories
Parameters
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