Coding
SYB15

Part:BBa_K3653002

Designed by: Ella Samuel, Shanny Ackerman   Group: iGEM20_Technion-Israel   (2020-10-11)


Sybody 15 - A synthetic single domain nanobody that targets SARS-CoV-2 spike proteins.

Sybodies are small-sized synthetic nanobodies (camelid single-domain antibodies) with a specific and high affinity to only one cognate target. Normally they are easy to produce, stable, soluble in aqueous solutions, and can refold without additional improvements. These specific Sybodies target the receptor-binding domain (RBD) of the SARS-CoV-2 spike proteins.

Sequence and Features


Assembly Compatibility:
  • 10
    INCOMPATIBLE WITH RFC[10]
    Illegal EcoRI site found at 249
  • 12
    INCOMPATIBLE WITH RFC[12]
    Illegal EcoRI site found at 249
  • 21
    INCOMPATIBLE WITH RFC[21]
    Illegal EcoRI site found at 249
  • 23
    INCOMPATIBLE WITH RFC[23]
    Illegal EcoRI site found at 249
  • 25
    INCOMPATIBLE WITH RFC[25]
    Illegal EcoRI site found at 249
  • 1000
    COMPATIBLE WITH RFC[1000]


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Categories
Parameters
None