Coding

Part:BBa_K3498004

Designed by: Ra�l Acosta Murillo   Group: iGEM20_FCB-UANL   (2020-09-17)


AbrB protein inhibits B. subtilis sporulation

The AbrB protein of the spore-forming bacterium Bacillus subtilis is a repressor of numerous that is present in vegetatively growing cells and is inactivated or eliminated by the action of Spo0A at the end of the exponential phase of growth; AbrB is a DNA-binding protein that acts by repressing target genes (Banse et al., 2008) . This part can be used for inhibiting biofilm and sporulation formation in B. subtilis, it affects the production by binding into DNA and blocking transcription. It affects more than +100 genes as it is a major regulator (Zhu & Stülke, 2017).

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]
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Categories
Parameters
None