Regulatory

Part:BBa_K2680526

Designed by: Julia Urban   Group: iGEM18_William_and_Mary   (2018-10-12)


pLsrR Promoter

pLsrR promoter. LsrR represses the lsr operon, a quorum sensing operon that processes Autoinducer-2 (AI-2). When phosphorylated AI-2 (phosphorus-AI-2) binds to LsrR, LsrR deactivates and no longer represses the lsr operon.1

William and Mary iGEM encountered the promoter for lsrA through our collaboration with Virginia iGEM. For more information, visit [http://2018.igem.org/Team:Virginia/Parts Virginia iGEM's wiki].

References

1Xavier, K. B., & Bassler, B. L. (2005). Regulation of Uptake and Processing of the Quorum-Sensing Autoinducer AI-2 in Escherichia coli. Journal of Bacteriology, 187(1), 238–248. http://doi.org/10.1128/JB.187.1.238-248.2005


Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


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Categories
Parameters
None