Protein_Domain

Part:BBa_K2401010

Designed by: Shanti Ricke   Group: iGEM17_Hamburg   (2017-10-21)


TonB dependent Siderophore Receptor fyuA: Yersiniabactin receptor

FyuA encodes for the TonB dependent outer membrane receptor for the bacterial siderophore yersiniabactin. It mediates the uptake of yersiniabactin-iron-complex from the surrounding media.

Studies found that fyuA must be an important factor in biofilm formation and therefore an important survival factor for bacteria in iron-deprived environments. FyuA Knockouts show extremely low biofilm formation capacities, which makes fyuA an interesting target for antimicrobial approaches.

On the other hand fyuA could be utilized to create strains of enterobacteriae on which siderophore therapies could be tested.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


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Categories
Parameters
None