Composite

Part:BBa_K2152002

Designed by: Shenjian Ai   Group: iGEM16_ShanghaiTechChina_B   (2016-10-13)


CsgA-EGF

Through molecular programming of the bacterial extracellular matrix material by genetically appending EGF peptide to the amyloid protein CsgA, the dominant proteinaceous component in E. coli biofilms. These engineered CsgA fusion proteins are successfully secreted and extracellularly self-assemble into amyloid nanofibrer networks that retain the functions of the displayed peptide domains. It may be able to use the function of EGF to treat IBD.


Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    INCOMPATIBLE WITH RFC[21]
    Illegal BglII site found at 615
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


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Categories
Parameters
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