Regulatory

Part:BBa_K1922001

Designed by: Jiawei Zhang   Group: iGEM16_Tongji_Shanghai   (2016-10-11)


Htert promoter

This is a promoter starting the expression of telomerase,an important enzyme to keep the telomere from being shortern during the cell proliferation.Since the tumor cell requires rapid cell proliferation,the content of telomerase is usually detected higher than normal cell.Therefore, we can use the Htert promoter as a cancer specific promoter to start downstream gene expresses only in tumor cell.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    INCOMPATIBLE WITH RFC[1000]
    Illegal BsaI site found at 263


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Categories
Parameters
None