Regulatory
Part:BBa_K1922001
Designed by: Jiawei Zhang Group: iGEM16_Tongji_Shanghai (2016-10-11)
Htert promoter
This is a promoter starting the expression of telomerase,an important enzyme to keep the telomere from being shortern during the cell proliferation.Since the tumor cell requires rapid cell proliferation,the content of telomerase is usually detected higher than normal cell.Therefore, we can use the Htert promoter as a cancer specific promoter to start downstream gene expresses only in tumor cell.
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000INCOMPATIBLE WITH RFC[1000]Illegal BsaI site found at 263
[edit]
Categories
Parameters
None |