Translational_Unit
leuB

Part:BBa_K1893027

Designed by: Henry Lloyd-Laney, Stefan Grossfurthner   Group: iGEM16_Imperial_College   (2016-10-14)


3-isopropylmalate dehydrogenase (leuB)

This part encodes for 3-isopropylmalate dehydrogenase, an enzyme in the leucine biosynthesis pathway of Escherichia coli that catalyses the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate. The leucine biosynthesis pathway is activated in conditions of leucine starvation and can exploited for use in auxotrophy systems.


Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


[edit]
Categories
Parameters
None