Coding

Part:BBa_K1892000

Designed by: YingQi Wang   Group: iGEM16_SMS_Shenzhen   (2016-10-13)


yebf (a motor protein) + LL-37

This is a part with only the coding sequence of yebf fused with LL-37. LL-37(also known as CAMP cathelicidin antimicrobial peptide, CAP18; CRAMP; HSD26; CAP-18; FALL39; FALL-39)is a Human antimicrobial peptide and the only member of Cathelicidin AMP family found in the human body. LL-37 is able to kill Gram negative and Gram positive bacteria, enveloped viruses, fungi, and even transformed or cancerous cells. yebf is a motor protein from Escherichia coli (strain K12). It can transport proteins fused to it through the bacterial cell membrane. In this case, yebf can transport LL-37 out of the cell membrane.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


[edit]
Categories
Parameters
None