Part:BBa_K1890056

BolA

Usdage and Biology

BolA is a gene that controls the morphology of Escherichia coli in the stress response [1]. By overexpressing this gene at 37°C, naturally rod-shaped E. coli cells will become spherical [2]. This biobrick contains the coding sequence of bolA, which is a subpart of BBa_K1890030 and BBa_K1890030. It does not exist individually.

References

[1] Santos, J. M., Freire, P., Vicente, M., & Arraiano, C. M. (1999). The stationary‐phase morphogene bolA from Escherichia coli is induced by stress during early stages of growth. Molecular microbiology, 32(4), 789-798.

[2] Aldea, M., Hernandez-Chico, C., De La Campa, A., Kushner, S., & Vicente, M. (1988). Identification, cloning, and expression of bolA, an ftsZ-dependent morphogene of Escherichia coli. Journal of bacteriology, 170(11), 5169-5176.