Protein_Domain
D1

Part:BBa_K1830009

Designed by: Mathieu Husser   Group: iGEM15_Concordia   (2015-08-06)

Dock1

Type I dockerin domain

Usage and Biology

Dock1 is the type I dockerin domain of the Cellulase S (CelS), part of the Clostridium Thermocellum cellulosome. The cellulosome is an extracellular protein scaffold that displays cellulose-degrading enzymes. These cellulases contain a dockerin domain that attaches to the cellulosome through cohesin/dockerin binding interactions. These interactions are calcium ion dependant and binding is specific, therefore a type I cohesin will only bind to a type I dockerin.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


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Categories
Parameters
None