Part:BBa_K1613019
It can detect methyl mercury.
MerB can turn Methyl mercury into Hg2+.MerR can combine with Hg2+ and change the structure of DNA. And DNA can be trancripted easier. PmerT is controlled by MerR. PmerT cannot be transcripted because MerR changes the shape of PmerT. In short, the whole reaction will continue if MerR combines with Hg2+.
Why do we detect mercury? Normally, there is no excess heavy metal in edible oil. Ingested mercury will hoard in the organs. Some recycled oil is made from animal internal organs. After mercury enters our body, it cannot be metabolized effectively and this leads to serious diseases. Due to the reasons above, we decided to detect this heavy metal.
The harm of mercury Methyl mercury is a type of neurotoxin. It represses cell division and restricts motility of electronic ions. It can also interfere with growing brain structure. Besides, methyl mercury can result in cardiovascular diseases like myocardial infarction, ischemic heart disease, hypertension and irregular pulse.
Sequence and Features
- 10COMPATIBLE WITH RFC[10]
- 12INCOMPATIBLE WITH RFC[12]Illegal NheI site found at 7
Illegal NheI site found at 30 - 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25INCOMPATIBLE WITH RFC[25]Illegal NgoMIV site found at 476
Illegal AgeI site found at 1790
Illegal AgeI site found at 1902 - 1000COMPATIBLE WITH RFC[1000]
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