Coding

Part:BBa_K1530000

Designed by: Yao Chin Liu   Group: iGEM14_Auckland_New_Zealand   (2014-12-17)


Homo sapiens (Human) Epithelial Cadherin Extracellular Domain

Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner.

This part consists of the extracellular domain of human E-Cadherin, so this part has the potential to either interact with another one of this part or with the E-Cadherin of human cells.

As such, this part is an ideal mechanism to use in engineering cell to cell adhesion or adhesion to human epithelial cells.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    INCOMPATIBLE WITH RFC[21]
    Illegal BamHI site found at 3
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    INCOMPATIBLE WITH RFC[25]
    Illegal AgeI site found at 129
    Illegal AgeI site found at 183
    Illegal AgeI site found at 519
    Illegal AgeI site found at 543
    Illegal AgeI site found at 1167
    Illegal AgeI site found at 1278
  • 1000
    COMPATIBLE WITH RFC[1000]


[edit]
Categories
Parameters
None