Translational_Unit

Part:BBa_K1202106

Designed by: safa tapan   Group: iGEM13_ATOMS-Turkiye   (2013-09-24)

TAT-HA2-Apoptin: Cancer killing peptide

HA2 peptide sequence is demonstrated that, with the combination of TAT, the cell penetrating activity increases considerably. We added HA2 in our TAT-Apoptin system to empower the yield of cancer killing mechanism.

Apoptin is a novel prospective cancer drug which induces programmed cell death (apoptosis) phase of normal cell life cycle in cancer cells, selectively. The exact mechanism of apoptin is not understood, yet. But, the efficiency and results of the function are researched and pose promising hopeful results for efficient cancer therapy.


Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    INCOMPATIBLE WITH RFC[12]
    Illegal NheI site found at 7
    Illegal NheI site found at 30
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    INCOMPATIBLE WITH RFC[25]
    Illegal AgeI site found at 462
  • 1000
    COMPATIBLE WITH RFC[1000]


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Categories
Parameters
None