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Regulatory
P(nirB)

Part:BBa_K1155004

Designed by: Solenne Ithurbide, Abdou, Anas, Zhu   Group: iGEM13_Paris_Saclay   (2013-09-13)

Promoter of nirB, activated by FNR in anaerobic conditions

Promoter of gene nirB from E. coli. Activated by FNR in anaerobic conditions and inactivated in aerobic conditions.

The promoter of the gene nirB is regulated by FNR. It's a class II promoter with two FNR boxes. (Scott et al, FEBS letter, 2003)

Aerobic conditions: +O2 --> FNR inactivated --> Promoter non activated Anaerobic conditions: - O2 --> FNR activated --> Promoter activated

P(nirB) is predicted to be highly induced under anaerobic conditions :48-64 fold. (Lolesnikow et al, J. bacteriol 1992 / Griffiths et al, Arch. Microbiol. 1987 / Green et al, Mol. Microbiol, 1998)


Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


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