Protein domains/Overview
Revision as of 01:37, 27 March 2009 by Rshetty (Talk | contribs) (Protein tags and modifiers/Overview moved to Protein domains, tags and modifiers/Overview)
Protein tags and modifiers are short peptide sequences cloned in frame with protein coding sequences that change the protein's behavior.
Protein tags and modifiers might
- change the protein's location (localization signals)
- enable it to be readily purified (affinity tags)
- fuse two protein domains together (linkers)
- alter the protein's degradation rate (degradation tags)
- target the protein for cleavage (cleavage sites)
Protein tags may include a start codon or a stop codon, but not both, since they are intended to be assembled in frame with protein coding sequences (?).