Part:BBa_K4781005

Tat E - A protein of the TAT pathway complex

Tat protein TatE that is homologous to the TatA protein is present at a much lower level in the cell than TatA. In Escherichia coli and other Gram-negative bacteria, TatA, TatB, and TatC are all essential for efficient translocation. The twin arginine translocase (Tat) is a protein transport pathway that exists in archaea, bacteria, and plant chloroplasts. In bacteria, it exports proteins across the plasma membrane and is important for many processes, including energy metabolism, formation of the cell envelope, biofilm formation, heavy metal resistance, nitrogen-fixing symbiosis, bacterial pathogenesis and others [1], [2]. What makes this protein transport system unusual compared to other transport systems (such as the general secretory, or Sec pathway) is its ability to transport fully folded proteins across membranes. This remarkable feat has no requirement for ATP as an energy source and relies solely on the proton motive force (PMF).

Sequence and Features

Assembly Compatibility:

• 10
  COMPATIBLE WITH RFC[10]
• 12
  COMPATIBLE WITH RFC[12]
• 21
  COMPATIBLE WITH RFC[21]
• 23
  COMPATIBLE WITH RFC[23]
• 25
  COMPATIBLE WITH RFC[25]
• 1000
  INCOMPATIBLE WITH RFC[1000]

  Illegal BsaI.rc site found at 89