Part:BBa_K4781004
Tat C - A protein of the TAT pathway complex
In Escherichia coli and other Gram-negative bacteria, TatA, TatB, and TatC are all essential for efficient translocation.The twin arginine translocase (Tat) is a protein transport pathway that exists in archaea, bacteria, and plant chloroplasts. In bacteria, it exports proteins across the plasma membrane and is important for many processes, including energy metabolism, formation of the cell envelope, biofilm formation, heavy metal resistance, nitrogen-fixing symbiosis, bacterial pathogenesis and others [1], [2]. What makes this protein transport system unusual compared to other transport systems (such as the general secretory, or Sec pathway) is its ability to transport fully folded proteins across membranes. This remarkable feat has no requirement for ATP as an energy source and relies solely on the proton motive force (PMF).
Sequence and Features
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25INCOMPATIBLE WITH RFC[25]Illegal NgoMIV site found at 288
- 1000COMPATIBLE WITH RFC[1000]
| biology | TatC is the largest and most highly conserved Tat component. The E. coli TatC is a 258-amino-acid polytopic membrane protein with six TM helices and both the N and C termini located on the cytoplasmic side of the membrane |
| chassis | E.coli |
| uniprot | P69423 |