Coding

Part:BBa_J52035

Designed by: Ota Fekonja   Group: iGEM2006_Slovenia   (2006-10-15)

dnMyD88

dnMyD88 is a dominant negative form of MyD88, which has an important role in TLR signaling pathway. dnMyD88 contains only the TIR domain of MyD88.

This part played a key role in the winning project in the 2006 iGEM competition. See the description on the Ljubljana (Slovenia) team's [http://parts2.mit.edu/wiki/index.php/Ljubljana%2C_Slovenia_2006 webpage].


Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


[edit]
Categories
//cds/membrane/receptor
//function/immunology
Parameters
None